Ontology highlight
ABSTRACT:
SUBMITTER: Batista MN
PROVIDER: S-EPMC6356660 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Viruses 20190111 1
Zika virus (ZIKV) has been associated with serious health conditions, and an intense search to discover different ways to prevent and treat ZIKV infection is underway. Berberine and emodin possess several pharmacological properties and have been shown to be particularly effective against the entry and replication of several viruses. We show that emodin and berberine trigger a virucidal effect on ZIKV. When the virus was exposed to 160 µM of berberine, a reduction of 77.6% in the infectivity was ...[more]