Circulating Biomarkers for Prediction of Objective Response to Chemotherapy in Pancreatic Cancer Patients.
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ABSTRACT:
SUBMITTER: van der Sijde F
PROVIDER: S-EPMC6356815 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Publications
Circulating Biomarkers for Prediction of Objective Response to Chemotherapy in Pancreatic Cancer Patients.
van der Sijde Fleur F Vietsch Eveline E EE Mustafa Dana A M DAM Besselink Marc G MG Groot Koerkamp Bas B van Eijck Casper H J CHJ
Cancers 20190115 1
Pancreatic cancer is a lethal disease with increasing incidence. Most patients present with advanced disease, for which palliative systemic chemotherapy is the only therapeutic option. Despite improved median survival rates with FOLFIRINOX or gemcitabine chemotherapy compared to the best supportive care, many individual patients may not benefit from chemotherapy. Biomarkers are needed to predict who will benefit from chemotherapy and to monitor a patient's response to chemotherapy. This review s ...[more]
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