Ontology highlight
ABSTRACT:
SUBMITTER: Hiramatsu K
PROVIDER: S-EPMC6357763 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Hiramatsu Kotaro K Ideguchi Takuro T Yonamine Yusuke Y Lee SangWook S Luo Yizhi Y Hashimoto Kazuki K Ito Takuro T Hase Misa M Park Jee-Woong JW Kasai Yusuke Y Sakuma Shinya S Hayakawa Takeshi T Arai Fumihito F Hoshino Yu Y Goda Keisuke K
Science advances 20190116 1
Flow cytometry is an indispensable tool in biology for counting and analyzing single cells in large heterogeneous populations. However, it predominantly relies on fluorescent labeling to differentiate cells and, hence, comes with several fundamental drawbacks. Here, we present a high-throughput Raman flow cytometer on a microfluidic chip that chemically probes single live cells in a label-free manner. It is based on a rapid-scan Fourier-transform coherent anti-Stokes Raman scattering spectromete ...[more]