Prognostic role of early D-dimer level in patients with acute ischemic stroke.

ABSTRACT: OBJECT:The purpose of our study was to assess the prognostic role of early D-dimer level in patients with acute ischemic stroke (AIS). METHODS:The included patients' D-dimer levels have to be tested within 24 hours from stroke onset. Poor functional outcome was defined as modified Rankin Scale (mRS) ≥3. The endpoints included recurrence on 5-day diffusion-weighted imaging, 30-day mRS ≥3, 30-day mortality and 90-day mRS ≥3. Regarding to each endpoint, odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the prognostic role of D-dimer in patients with AIS. RESULTS:A total of 2,479 patients were included. The results showed that elevated D-dimer levels were associated with recurrence on 5-day diffusion-weighted imaging (OR = 2.28, 95% CI = 1.32-3.95), 30-day mRS≥3 (O

SUBMITTER: Zhang J 

PROVIDER: S-EPMC6358072 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature