Ontology highlight
ABSTRACT:
SUBMITTER: Bucciol G
PROVIDER: S-EPMC6358521 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
The Journal of allergy and clinical immunology 20180801 2
Innate immunity contributes to host defense through all cell types and relies on their shared germline genetic background, whereas adaptive immunity operates through only 3 main cell types, αβ T cells, γδ T cells, and B cells, and relies on their somatic genetic diversification of antigen-specific responses. Human inborn errors of innate immunity often underlie infectious diseases. The range and nature of infections depend on the mutated gene, the deleteriousness of the mutation, and other ill-d ...[more]