Ontology highlight
ABSTRACT:
SUBMITTER: Yasuda K
PROVIDER: S-EPMC6358604 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Nature communications 20190201 1
The genome organizer, special AT-rich sequence-binding protein-1 (Satb1), plays a pivotal role in the regulation of global gene networks in a cell type-dependent manner and is indispensable for the development of multiple cell types, including mature CD4<sup>+</sup> T, CD8<sup>+</sup> T, and Foxp3<sup>+</sup> regulatory T cells in the thymus. However, it remains unknown how the differentiation and effector program of the Th subsets in the periphery are regulated by Satb1. Here, we demonstrate th ...[more]