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Microwave-Assisted Dehydrogenative Cross Coupling Reactions in ?-valerolactone with a Reusable Pd/?-cyclodextrin Crosslinked Catalyst.

ABSTRACT: Transition-metal mediated C?H bond activation and functionalization is one of the most straightforward and powerful tools in modern organic synthetic chemistry. Oxidative C?H/C?H coupling reactions between two (hetero)arenes under heterogeneous catalysis may be a valuable means for the production of a plethora of bi(hetero)aryls, and one that adheres to the increasing demand for atom-economic and sustainable chemistry. We have therefore developed a reusable heterogeneous catalytic system, which is based on Pd cross-linked ?-cyclodextrin, to perform an efficient microwave-assisted oxidative C?H/C?H cross coupling process between benzothiazoles and methyl thiophene in the presence of green solvents.

SUBMITTER: Tabasso S

PROVIDER: S-EPMC6359118 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Microwave-Assisted Dehydrogenative Cross Coupling Reactions in γ-valerolactone with a Reusable Pd/β-cyclodextrin Crosslinked Catalyst.

Tabasso Silvia S Gaudino Emanuela Calcio EC Acciardo Elisa E Manzoli Maela M Giacomino Agnese A Cravotto Giancarlo G

Molecules (Basel, Switzerland) 20190114 2

Transition-metal mediated C⁻H bond activation and functionalization is one of the most straightforward and powerful tools in modern organic synthetic chemistry. Oxidative C⁻H/C⁻H coupling reactions between two (hetero)arenes under heterogeneous catalysis may be a valuable means for the production of a plethora of bi(hetero)aryls, and one that adheres to the increasing demand for atom-economic and sustainable chemistry. We have therefore developed a reusable heterogeneous catalytic system, which ...[more]

PMID: 30646596

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