Ontology highlight
ABSTRACT:
SUBMITTER: Hanif M
PROVIDER: S-EPMC6359172 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Hanif Muhammad M Kanwal Fariha F Rafiq Muhammad M Hassan Mubashir M Mustaqeem Muhammad M Seo Sung-Yum SY Zhang Yunlong Y Lu Changrui C Chen Ting T Saleem Muhammad M
Molecules (Basel, Switzerland) 20190116 2
The present study focuses on the design and synthesis of a cage-like organic skeleton containing two triazole rings jointed via imine linkage. These molecules can act as urease inhibitors. The in-vitro urease inhibition screening results showed that the combination of the two triazole skeleton in the cage-like morphology exhibited comparable urease inhibition activity to that of the reference thiourea while the metallic complexation, especially with copper, nickel, and palladium, showed excellen ...[more]