Ontology highlight
ABSTRACT:
SUBMITTER: Vanhove K
PROVIDER: S-EPMC6359540 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Vanhove Karolien K Derveaux Elien E Graulus Geert-Jan GJ Mesotten Liesbet L Thomeer Michiel M Noben Jean-Paul JP Guedens Wanda W Adriaensens Peter P
International journal of molecular sciences 20190110 2
Lung cancer cells are well-documented to rewire their metabolism and energy production networks to support rapid survival and proliferation. This metabolic reorganization has been recognized as a hallmark of cancer. The increased uptake of glucose and the increased activity of the glycolytic pathway have been extensively described. However, over the past years, increasing evidence has shown that lung cancer cells also require glutamine to fulfill their metabolic needs. As a nitrogen source, glut ...[more]