Ontology highlight
ABSTRACT:
SUBMITTER: Gong HT
PROVIDER: S-EPMC6362516 | biostudies-literature | 2019 Jan-Mar
REPOSITORIES: biostudies-literature
Journal of the renin-angiotensin-aldosterone system : JRAAS 20190101 1
<h4>Introduction:</h4>This study aimed to investigate whether mononucleotide polymorphisms of the angiotensinogen gene at promoter were associated with the blood-pressure-lowering response to telmisartan treatment.<h4>Materials and methods:</h4>After a two-week single-blind placebo run-in period, 148 patients with mild-to-moderate primary hypertension received monotherapy with 80 mg/day of telmisartan and then were followed up for eight weeks. The -6A/G and -20A/C polymorphisms of the angiotensi ...[more]