Ontology highlight
ABSTRACT:
SUBMITTER: Heffley W
PROVIDER: S-EPMC6362851 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Heffley William W Song Eun Young EY Xu Ziye Z Taylor Benjamin N BN Hughes Mary Anne MA McKinney Andrew A Joshua Mati M Hull Court C
Nature neuroscience 20180917 10
The prevailing model of cerebellar learning states that climbing fibers (CFs) are both driven by, and serve to correct, erroneous motor output. However, this model is grounded largely in studies of behaviors that utilize hardwired neural pathways to link sensory input to motor output. To test whether this model applies to more flexible learning regimes that require arbitrary sensorimotor associations, we developed a cerebellar-dependent motor learning task that is compatible with both mesoscale ...[more]