Dataset Information

Corticospinal excitability during fatiguing whole body exercise.

ABSTRACT: The corticospinal pathway is considered the primary conduit for voluntary motor control in humans. The efficacy of the corticospinal pathway to relay neural signals from higher brain areas to the locomotor muscle, i.e., corticospinal excitability, is subject to alterations during exercise. While the integrity of this motor pathway has historically been examined during single-joint contractions, a small number of investigations have recently focused on whole body exercise, such as cycling or rowing. Although differences in methodologies employed between these studies complicate the interpretation of the existing literature, it appears that the net excitability of the corticospinal pathway remains unaltered during fatiguing whole body exercise. Importantly, this lack of an apparent effect does not designate the absence of change, but a counterbalance of excitatory and inhibitory influences on the two components of the corticospinal pathway, namely the motor cortex and the spinal motoneurons. Specific emphasis is put on group III/IV afferent feedback from locomotor muscle which has been suggested to play a significant role in mediating these changes. Overall, this review aims at summarizing our limited understanding of how fatiguing whole body exercise influences the corticospinal pathway.

SUBMITTER: Weavil JC

PROVIDER: S-EPMC6363483 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Corticospinal excitability during fatiguing whole body exercise.

Weavil Joshua C JC Amann Markus M

Progress in brain research 20180917

The corticospinal pathway is considered the primary conduit for voluntary motor control in humans. The efficacy of the corticospinal pathway to relay neural signals from higher brain areas to the locomotor muscle, i.e., corticospinal excitability, is subject to alterations during exercise. While the integrity of this motor pathway has historically been examined during single-joint contractions, a small number of investigations have recently focused on whole body exercise, such as cycling or rowi ...[more]

PMID: 30390833

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Project description:Direct gaze is a powerful social cue able to capture the onlooker's attention. Beside gaze, head and limb movements as well can provide relevant sources of information for social interaction. This study investigated the joint role of direct gaze and hand gestures on onlookers corticospinal excitability (CE). In two experiments we manipulated the temporal and spatial aspects of observed gaze and hand behavior to assess their role in affecting motor preparation. To do this, transcranial magnetic stimulation (TMS) on the primary motor cortex (M1) coupled with electromyography (EMG) recording was used in two experiments. In the crucial manipulation, we showed to participants four video clips of an actor who initially displayed eye contact while starting a social request gesture, and then completed the action while directing his gaze toward a salient object for the interaction. This way, the observed gaze potentially expressed the intention to interact. Eye tracking data confirmed that gaze manipulation was effective in drawing observers' attention to the actor's hand gesture. In the attempt to reveal possible time-locked modulations, we tracked CE at the onset and offset of the request gesture. Neurophysiological results showed an early CE modulation when the actor was about to start the request gesture looking straight to the participants, compared to when his gaze was averted from the gesture. This effect was time-locked to the kinematics of the actor's arm movement. Overall, data from the two experiments seem to indicate that the joint contribution of direct gaze and precocious kinematic information, gained while a request gesture is on the verge of beginning, increases the subjective experience of involvement and allows observers to prepare for an appropriate social interaction. On the contrary, the separation of gaze cues and body kinematics can have adverse effects on social motor preparation. CE is highly susceptible to biological cues, such as averted gaze, which is able to automatically capture and divert observer's attention. This point to the existence of heuristics based on early action and gaze cues that would allow observers to interact appropriately.

Dataset Information

Corticospinal excitability during fatiguing whole body exercise.

Publications

Corticospinal excitability during fatiguing whole body exercise.

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