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Quality of life and symptom burden among myeloproliferative neoplasm patients: do symptoms impact quality of life?


ABSTRACT: Patients with myeloproliferative neoplasms (MPNs) are faced with high disease-related symptom burden and quality of life (QoL) decrements. This analysis assesses the extent to which individual symptoms or summary measures across symptoms impact QoL overall and within MPN subgroups. Four sets of summary measures were constructed assessing symptom prevalence and severity within group-standardized and patient-individualized approaches. Among 1416 international patients with MPNs, mean symptom severity and prevalence were highly correlated (p?

SUBMITTER: Langlais BT 

PROVIDER: S-EPMC6363896 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Quality of life and symptom burden among myeloproliferative neoplasm patients: do symptoms impact quality of life?

Langlais Blake T BT   Geyer Holly H   Scherber Robyn R   Mesa Ruben A RA   Dueck Amylou C AC  

Leukemia & lymphoma 20180722 2


Patients with myeloproliferative neoplasms (MPNs) are faced with high disease-related symptom burden and quality of life (QoL) decrements. This analysis assesses the extent to which individual symptoms or summary measures across symptoms impact QoL overall and within MPN subgroups. Four sets of summary measures were constructed assessing symptom prevalence and severity within group-standardized and patient-individualized approaches. Among 1416 international patients with MPNs, mean symptom sever  ...[more]

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