Polyphyly in 16S rRNA-based LVTree Versus Monophyly in Whole-genome-based CVTree.
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ABSTRACT:
SUBMITTER: Zuo G
PROVIDER: S-EPMC6364046 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
Polyphyly in 16S rRNA-based LVTree Versus Monophyly in Whole-genome-based CVTree.
Zuo Guanghong G Qi Ji J Hao Bailin B
Genomics, proteomics & bioinformatics 20181001 5
We report an important but long-overlooked manifestation of low-resolution power of 16S rRNA sequence analysis at the species level, namely, in 16S rRNA-based phylogenetic trees polyphyletic placements of closely-related species are abundant compared to those in genome-based phylogeny. This phenomenon makes the demarcation of genera within many families ambiguous in the 16S rRNA-based taxonomy. In this study, we reconstructed phylogenetic relationship for more than ten thousand prokaryote genome ...[more]
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