Ontology highlight
ABSTRACT:
SUBMITTER: Rosenkilde CEH
PROVIDER: S-EPMC6365502 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Rosenkilde Carola E H CEH Munck Christian C Porse Andreas A Linkevicius Marius M Andersson Dan I DI Sommer Morten O A MOA
Nature communications 20190206 1
Antibiotic resistance is a major challenge to global public health. Discovery of new antibiotics is slow and to ensure proper treatment of bacterial infections new strategies are needed. One way to curb the development of antibiotic resistance is to design drug combinations where the development of resistance against one drug leads to collateral sensitivity to the other drug. Here we study collateral sensitivity patterns of the globally distributed extended-spectrum β-lactamase CTX-M-15, and fin ...[more]