Ontology highlight
ABSTRACT:
SUBMITTER: Monaco G
PROVIDER: S-EPMC6367568 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Monaco Gianni G Lee Bernett B Xu Weili W Mustafah Seri S Hwang You Yi YY Carré Christophe C Burdin Nicolas N Visan Lucian L Ceccarelli Michele M Poidinger Michael M Zippelius Alfred A Pedro de Magalhães João J Larbi Anis A
Cell reports 20190201 6
The molecular characterization of immune subsets is important for designing effective strategies to understand and treat diseases. We characterized 29 immune cell types within the peripheral blood mononuclear cell (PBMC) fraction of healthy donors using RNA-seq (RNA sequencing) and flow cytometry. Our dataset was used, first, to identify sets of genes that are specific, are co-expressed, and have housekeeping roles across the 29 cell types. Then, we examined differences in mRNA heterogeneity and ...[more]