Ontology highlight
ABSTRACT:
SUBMITTER: Burgers J
PROVIDER: S-EPMC6368534 | biostudies-literature | 2019 Jan
REPOSITORIES: biostudies-literature
Neurophotonics 20190101 1
The goal of understanding the architecture of neural circuits at the synapse level with a brain-wide perspective has powered the interest in high-speed and large field-of-view volumetric imaging at subcellular resolution. Here, we developed a method combining tissue expansion and light-sheet fluorescence microscopy to allow extended volumetric super resolution high-speed imaging of large mouse brain samples. We demonstrate the capabilities of this method by performing two color fast volumetric s ...[more]