Dataset Information

Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety.

ABSTRACT:

Purpose

To perform an evaluation on safety and efficacy of uterine artery embolization (UAE) in the patients with symptomatic cervical leiomyomata.

Methods

Patients with symptomatic cervical leiomyomata who underwent UAE in one specialized hospital were retrospectively analyzed, both clinically and with MR imaging. The 3-month outcomes were assessed with MR imaging and a validated questionnaire. Long-term follow-up was assessed by direct contact or file review. To determine the efficacy of UAE for cervical leiomyomata, the primary objective was to assess the clinical outcome with the UFS-QOL questionnaire, containing the health-related quality of life (HRQOL) and symptom severity score (SSS). To assess safety, the secondary objective included leiomyomata volume reduction, the infarction/complication rate and secondary interventions were needed.

Results

Between 2006 and 2017, eight of 1180 patients underwent UAE and were eligible for inclusion. All embolizations were technically successful (n?=?8). At 3 months, all patients showed cervical leiomyomata volume reduction with a median reduction of 41.5% (38.8 cm³) compared to baseline (p?=?0.012). No complications occurred. At a median follow-up of 3 months (range 1-7, n?=?7), the HRQOL and SSS improved with a median difference of 13 points (range -?5 to 60, p?=?0.063) and -?13 points (range -?79 to 3, p?=?0.046), respectively. Long-term follow-up showed two secondary interventions (median of 43.5 months). Six patients reported no symptom recurrence.

Conclusion

UAE in women with symptomatic cervical leiomyomata is effective and safe with significant improvement in symptoms and quality of life. UAE is a valuable option for women seeking a non-surgical solution.

SUBMITTER: de Bruijn AM

PROVIDER: S-EPMC6373190 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety.

de Bruijn Annefleur M AM Adriaansens Sven-Ole J H SJH Smink Marieke M Venmans Alexander A Hehenkamp Wouter J K WJK Smeets Albert J AJ Lopez Anthony A Huirne Judith A F JAF Lohle Paul N M PNM

Cardiovascular and interventional radiology 20181004 3

<h4>Purpose</h4>To perform an evaluation on safety and efficacy of uterine artery embolization (UAE) in the patients with symptomatic cervical leiomyomata.<h4>Methods</h4>Patients with symptomatic cervical leiomyomata who underwent UAE in one specialized hospital were retrospectively analyzed, both clinically and with MR imaging. The 3-month outcomes were assessed with MR imaging and a validated questionnaire. Long-term follow-up was assessed by direct contact or file review. To determine the ef ...[more]

PMID: 30288591

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Dataset Information

Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety.

Purpose

Methods

Results

Conclusion

Publications

Uterine Artery Embolization in Women with Symptomatic Cervical Leiomyomata: Efficacy and Safety.

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