Ontology highlight
ABSTRACT:
SUBMITTER: Grydeland H
PROVIDER: S-EPMC6373687 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Grydeland Håkon H Vértes Petra E PE Váša František F Romero-Garcia Rafael R Whitaker Kirstie K Alexander-Bloch Aaron F AF Bjørnerud Atle A Patel Ameera X AX Sederevicius Donatas D Tamnes Christian K CK Westlye Lars T LT White Simon R SR Walhovd Kristine B KB Fjell Anders M AM Bullmore Edward T ET
Cerebral cortex (New York, N.Y. : 1991) 20190301 3
Seminal human brain histology work has demonstrated developmental waves of myelination. Here, using a micro-structural magnetic resonance imaging (MRI) marker linked to myelin, we studied fine-grained age differences to deduce waves of growth, stability, and decline of cortical myelination over the life-cycle. In 484 participants, aged 8-85 years, we fitted smooth growth curves to T1- to T2-weighted ratio in each of 360 regions from one of seven cytoarchitectonic classes. From the first derivati ...[more]