Ontology highlight
ABSTRACT:
SUBMITTER: Lerman I
PROVIDER: S-EPMC6373934 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Lerman Imanuel I Davis Bryan B Huang Mingxiong M Huang Charles C Sorkin Linda L Proudfoot James J Zhong Edward E Kimball Donald D Rao Ramesh R Simon Bruce B Spadoni Andrea A Strigo Irina I Baker Dewleen G DG Simmons Alan N AN
PloS one 20190213 2
The mechanisms by which noninvasive vagal nerve stimulation (nVNS) affect central and peripheral neural circuits that subserve pain and autonomic physiology are not clear, and thus remain an area of intense investigation. Effects of nVNS vs sham stimulation on subject responses to five noxious thermal stimuli (applied to left lower extremity), were measured in 30 healthy subjects (n = 15 sham and n = 15 nVNS), with fMRI and physiological galvanic skin response (GSR). With repeated noxious therma ...[more]