Ontology highlight
ABSTRACT:
SUBMITTER: Moraes FY
PROVIDER: S-EPMC6374761 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Moraes Fabio Y FY Winter Jeff J Atenafu Eshetu G EG Dasgupta Archya A Raziee Hamid H Coolens Catherine C Millar Barbara-Ann BA Laperriere Normand N Patel Maitry M Bernstein Mark M Kongkham Paul P Zadeh Gelareh G Conrad Tatiana T Chung Caroline C Berlin Alejandro A Shultz David B DB
Neuro-oncology 20190201 2
<h4>Background</h4>At our institution, we have historically treated brain metastasis (BM) ≤2 cm in eloquent brain with a radiosurgery (SRS) lower prescription dose (PD) to reduce the risk of radionecrosis (RN). We sought to evaluate the impact of this practice on outcomes.<h4>Methods</h4>We analyzed a prospective registry of BM patients treated with SRS between 2008 and 2017. Incidences of local failure (LF) and RN were determined and Cox regression was performed for univariate and multivariate ...[more]