Dataset Information

Second-hand smoke exposure in adulthood and lower respiratory health during 20?year follow up in the European Community Respiratory Health Survey.

ABSTRACT:

Background

Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20?years.

Methods

We used information from 3011 adults from 26 centres in 12 countries who participated in the European Community Respiratory Health Surveys I-III and were never or former smokers at all three surveys. Associations of SHS exposure with respiratory health (asthma symptom score, asthma, chronic bronchitis, COPD) were analysed using generalised linear mixed-effects models adjusted for confounding factors (including sex, age, smoking status, socioeconomic status and allergic sensitisation). Linear mixed-effects models with additional adjustment for height were used to assess the relationships between SHS exposure and lung function levels and decline.

Results

Reported exposure to SHS decreased in all 26 study centres over time. The prevalence of SHS exposure was 38.7% at baseline (1990-1994) and 7.1% after the 20-year follow-up (2008-2011). On average 2.4% of the study participants were not exposed at the first, but were exposed at the third examination. An increase in SHS exposure over time was associated with doctor-diagnosed asthma (odds ratio (OR): 2.7; 95% confidence interval (95%-CI): 1.2-5.9), chronic bronchitis (OR: 4.8; 95%-CI: 1.6-15.0), asthma symptom score (count ratio (CR): 1.9; 95%-CI: 1.2-2.9) and dyspnoea (OR: 2.7; 95%-CI: 1.1-6.7) compared to never exposed to SHS. Associations between increase in SHS exposure and incidence of COPD (OR: 2.0; 95%-CI: 0.6-6.0) or lung function (?: -?49?ml; 95%-CI: -132, 35 for FEV₁ and ?: -?62?ml; 95%-CI: -165, 40 for FVC) were not apparent.

Conclusion

Exposure to second-hand smoke may lead to respiratory symptoms, but this is not accompanied by lung function changes.

SUBMITTER: Flexeder C

PROVIDER: S-EPMC6376659 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Publications

Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey.

Flexeder Claudia C Zock Jan-Paul JP Jarvis Deborah D Verlato Giuseppe G Olivieri Mario M Benke Geza G Abramson Michael J MJ Sigsgaard Torben T Svanes Cecilie C Torén Kjell K Nowak Dennis D Jõgi Rain R Martinez-Moratalla Jesús J Demoly Pascal P Janson Christer C Gislason Thorarinn T Bono Roberto R Holm Mathias M Franklin Karl A KA Garcia-Aymerich Judith J Siroux Valérie V Leynaert Bénédicte B Dorado Arenas Sandra S Corsico Angelo Guido AG Pereira-Vega Antonio A Probst-Hensch Nicole N Urrutia Landa Isabel I Schulz Holger H Heinrich Joachim J

Respiratory research 20190214 1

<h4>Background</h4>Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function decline in adulthood has not been widely investigated in longitudinal studies. Our aim is to investigate the associations of exposure to SHS in adults with respiratory symptoms, respiratory conditions and lung function over 20 years.<h4>Methods</h4>We used information from 3011 adults from 26 centres in 12 countries who ...[more]

PMID: 30764884

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