Procedure Preference and Intention-to-Treat Outcomes after Listing for Lung Transplantation among U.S. Adults. A Cohort Study.

ABSTRACT:

Rationale

Bilateral lung transplantation is widely used to treat chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD), on the basis of an expectation of improved survival after transplantation. Yet, waiting list mortality is higher while awaiting bilateral transplantation. The net effect of procedure preference on overall survival is unknown.

Objectives

To determine whether an unrestricted procedure preference is associated with improved overall outcomes after listing for lung transplantation.

Methods

We performed a retrospective cohort study of 12,155 adults with COPD or ILD listed for lung transplantation in the United States between May 4, 2005, and December 31, 2014. We defined a "restricted" procedure preference as listing for "bilater

SUBMITTER: Anderson MR 

PROVIDER: S-EPMC6376945 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature