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Mineral surfaces select for longer RNA molecules.


ABSTRACT: We report empirically and theoretically that multiple prebiotic minerals can selectively accumulate longer RNAs, with selectivity enhanced at higher temperatures. We further demonstrate that surfaces can be combined with a catalytic RNA to form longer RNA polymers, supporting the potential of minerals to develop genetic information on the early Earth.

SUBMITTER: Mizuuchi R 

PROVIDER: S-EPMC6377063 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature

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Mineral surfaces select for longer RNA molecules.

Mizuuchi Ryo R   Blokhuis Alex A   Vincent Lena L   Nghe Philippe P   Lehman Niles N   Baum David D  

Chemical communications (Cambridge, England) 20190201 14


We report empirically and theoretically that multiple prebiotic minerals can selectively accumulate longer RNAs, with selectivity enhanced at higher temperatures. We further demonstrate that surfaces can be combined with a catalytic RNA to form longer RNA polymers, supporting the potential of minerals to develop genetic information on the early Earth. ...[more]

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