Ontology highlight
ABSTRACT:
SUBMITTER: Dumm RE
PROVIDER: S-EPMC6377627 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Dumm Rebekah E RE Fiege Jessica K JK Waring Barbara M BM Kuo Chay T CT Langlois Ryan A RA Heaton Nicholas S NS
Nature communications 20190215 1
Influenza B virus (IBV) is an acute, respiratory RNA virus that has been assumed to induce the eventual death of all infected cells. We and others have shown however, that infection with apparently cytopathic viruses does not necessarily lead to cell death; some cells can intrinsically clear the virus and persist in the host long-term. To determine if any cells can survive direct IBV infection, we here generate a recombinant IBV capable of activating a host-cell reporter to permanently label all ...[more]