Multi-cohort study identifies social determinants of systemic inflammation over the life course.
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ABSTRACT:
SUBMITTER: Berger E
PROVIDER: S-EPMC6377676 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
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Multi-cohort study identifies social determinants of systemic inflammation over the life course.
Berger Eloïse E Castagné Raphaële R Chadeau-Hyam Marc M Bochud Murielle M d'Errico Angelo A Gandini Martina M Karimi Maryam M Kivimäki Mika M Krogh Vittorio V Marmot Michael M Panico Salvatore S Preisig Martin M Ricceri Fulvio F Sacerdote Carlotta C Steptoe Andrew A Stringhini Silvia S Tumino Rosario R Vineis Paolo P Delpierre Cyrille C Kelly-Irving Michelle M
Nature communications 20190215 1
Chronic inflammation has been proposed as having a prominent role in the construction of social inequalities in health. Disentangling the effects of early life and adulthood social disadvantage on inflammation is key in elucidating biological mechanisms underlying socioeconomic disparities. Here we explore the relationship between socioeconomic position (SEP) across the life course and inflammation (as measured by CRP levels) in up to 23,008 participants from six European cohort studies from thr ...[more]
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