Ontology highlight
ABSTRACT:
SUBMITTER: Stockdale L
PROVIDER: S-EPMC6378403 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Stockdale Lisa L Nash Stephen S Nalwoga Angela A Gibson Lorna L Painter Hannah H Raynes John J Asiki Gershim G Newton Robert R Fletcher Helen H
Tropical medicine & international health : TM & IH 20181227 2
<h4>Objectives</h4>A growing evidence base implicates human cytomegalovirus (HCMV) as a risk factor for TB disease. We investigated total IgG and mycobacteria-specific antibodies in a cross-sectional study nested within a rural Ugandan General Population Cohort (GPC), in relation to HIV infection and the magnitude of HCMV IgG response.<h4>Methods</h4>Sera from 2189 individuals (including 27 sputum-positive TB cases) were analysed for antibodies against mycobacteria (Ag85A, PPD, LAM, ESAT6/CFP10) ...[more]