Electromagnetic source imaging in presurgical workup of patients with epilepsy: A prospective study.

ABSTRACT:

Objective

To determine the diagnostic accuracy and clinical utility of electromagnetic source imaging (EMSI) in presurgical evaluation of patients with epilepsy.

Methods

We prospectively recorded magnetoencephalography (MEG) simultaneously with EEG and performed EMSI, comprising electric source imaging, magnetic source imaging, and analysis of combined MEG-EEG datasets, using 2 different software packages. As reference standard for irritative zone (IZ) and seizure onset zone (SOZ), we used intracranial recordings and for localization accuracy, outcome 1 year after operation.

Results

We included 141 consecutive patients. EMSI showed localized epileptiform discharges in 94 patients (67%). Most of the epileptiform discharge clusters (72%) were identified by both modaliti

SUBMITTER: Duez L 

PROVIDER: S-EPMC6382058 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature