Ontology highlight
ABSTRACT:
SUBMITTER: Turner TN
PROVIDER: S-EPMC6382467 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Turner Tychele N TN Eichler Evan E EE
Trends in neurosciences 20181215 2
Advances in sequencing technology have significantly expanded our understanding of the genetics of autism and neurodevelopmental disorders (NDDs). Continued technological improvements and cost reductions have now shifted the focus to investigations into the functional noncoding portions of the genome. There is a patient trend toward an excess of de novo and potentially disruptive mutations among conserved noncoding sequences implicated in the regulation of genes. The signals become stronger when ...[more]