Nutritional supplementation boosts aerobic exercise effects on functional brain systems.

ABSTRACT: There is growing evidence that aerobic exercise protects against age-related cognitive decline and that cardiorespiratory fitness is an important factor for these benefits. Studies also suggest that combining physical activity with cognitive enrichment is beneficial. We further examine these predictions by comparing effects of a nutritional supplement promoting exercise capacity to a lower-intensity activity with cognitive enrichment on functional network and cognitive outcomes that otherwise decline with aging. Inactive healthy older adults were randomized to one of four groups including a low-intensity activity with complex cognitive demands (dancing), walking, walking+supplement, or an active control. Results showed that walking+supplement increased salience network functional connectiv

SUBMITTER: Voss MW 

PROVIDER: S-EPMC6383642 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature