Dataset Information

New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement.

ABSTRACT:

Background and aims

Various studies have been previously conducted on the diagnosis of lymphadenopathy as benign or malignant, but the results vary. These studies did not describe the inter-rater agreement on the EUS features of lymphadenopathy. In this study, we evaluate the inter-rater agreement on EUS features and propose EUS diagnostic norms for lymphadenopathy based on inter-rater agreement.

Method

A total of 68 lymph nodes subjected to EUS-fine needle aspiration (FNA) were reviewed by five endoscopic experts. The EUS features evaluated lymph node size, shape, border, margin, echogenicity, homogeneity, and the hilum of the lymph node. Inter-rater agreement (multi-rater kappa statics) was performed. We established new criteria using results with a high degree of inter-rater agreement from EUS features and compared them with the former criteria.

Result

There was a moderate agreement on shape, kappa (K) = 0.44 (95% confidence interval [CI]: 0.34-0.54), and fair agreement on echogenicity, homogeneity, border, and hilum of the lymph node, K (95% CI) = 0.33 (0.17-0.38), 0.34 (0.26-0.35), 0.22 (0.21-0.31), and 0.22 (0.11-0.26), respectively. This resulted in the establishment of new EUS diagnostic criteria using shape, long axis > 20 mm and short axis > 10 mm. New criteria were superior to old criteria (area under the curve 0.82 vs 0.52, P < 0.001).

Conclusion

EUS diagnostic criteria for lymphadenopathy based on inter-rater agreement were more accurate than old criteria. This result will be useful for the diagnosis of lymphadenopathy.

SUBMITTER: Takasaki Y

PROVIDER: S-EPMC6386303 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

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Publications

New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement.

Takasaki Yusuke Y Irisawa Atsushi A Shibukawa Goro G Sato Ai A Abe Yoko Y Yamabe Akane A Arakawa Noriyuki N Maki Takumi T Yoshida Yoshitsugu Y Igarashi Ryo R Yamamoto Shogo S Ikeda Tsunehiko T

PloS one 20190222 2

<h4>Background and aims</h4>Various studies have been previously conducted on the diagnosis of lymphadenopathy as benign or malignant, but the results vary. These studies did not describe the inter-rater agreement on the EUS features of lymphadenopathy. In this study, we evaluate the inter-rater agreement on EUS features and propose EUS diagnostic norms for lymphadenopathy based on inter-rater agreement.<h4>Method</h4>A total of 68 lymph nodes subjected to EUS-fine needle aspiration (FNA) were r ...[more]

PMID: 30794598

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Dataset Information

New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement.

Background and aims

Method

Result

Conclusion

Publications

New endoscopic ultrasonography criteria for malignant lymphadenopathy based on inter-rater agreement.

Similar Datasets

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