Ontology highlight
ABSTRACT:
SUBMITTER: Wook Kim K
PROVIDER: S-EPMC6386807 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Wook Kim Ki K Allen Digby W DW Briese Thomas T Couper Jennifer J JJ Barry Simon C SC Colman Peter G PG Cotterill Andrew M AM Davis Elizabeth A EA Giles Lynne C LC Harrison Leonard C LC Harris Mark M Haynes Aveni A Horton Jessica L JL Isaacs Sonia R SR Jain Komal K Lipkin Walter Ian WI Morahan Grant G Morbey Claire C Pang Ignatius C N ICN Papenfuss Anthony T AT Penno Megan A S MAS Sinnott Richard O RO Soldatos Georgia G Thomson Rebecca L RL Vuillermin Peter J PJ Wentworth John M JM Wilkins Marc R MR Rawlinson William D WD Craig Maria E ME
Open forum infectious diseases 20190116 2
<h4>Background</h4>The importance of gut bacteria in human physiology, immune regulation, and disease pathogenesis is well established. In contrast, the composition and dynamics of the gut virome are largely unknown; particularly lacking are studies in pregnancy. We used comprehensive virome capture sequencing to characterize the gut virome of pregnant women with and without type 1 diabetes (T1D), longitudinally followed in the Environmental Determinants of Islet Autoimmunity study.<h4>Methods</ ...[more]