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Nanostructured Chemiresistive Gas Sensors for Medical Applications.

ABSTRACT: Treating diseases at their earliest stages significantly increases the chance of survival while decreasing the cost of treatment. Therefore, compared to traditional blood testing methods it is the goal of medical diagnostics to deliver a technique that can rapidly predict and if required non-invasively monitor illnesses such as lung cancer, diabetes, melanoma and breast cancer at their very earliest stages, when the chance of recovery is significantly higher. To date human breath nalysis is a promising candidate for fulfilling this need. Here, we highlight the latest key achievements on nanostructured chemiresistive sensors for disease diagnosis by human breath with focus on the multi-scale engineering of both composition and nano-micro scale morphology. We critically assess and compare state-of-the-art devices with the intention to provide direction for the next generation of chemiresistive nanostructured sensors.

SUBMITTER: Nasiri N

PROVIDER: S-EPMC6387115 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature

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Nanostructured Chemiresistive Gas Sensors for Medical Applications.

Nasiri Noushin N Clarke Christian C

Sensors (Basel, Switzerland) 20190123 3

Treating diseases at their earliest stages significantly increases the chance of survival while decreasing the cost of treatment. Therefore, compared to traditional blood testing methods it is the goal of medical diagnostics to deliver a technique that can rapidly predict and if required non-invasively monitor illnesses such as lung cancer, diabetes, melanoma and breast cancer at their very earliest stages, when the chance of recovery is significantly higher. To date human breath nalysis is a pr ...[more]

PMID: 30678070

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Project description:Day by day, the demand for portable, low cost, and efficient chemical/gas-sensing devices is increasing due to worldwide industrial growth for various purposes such as environmental monitoring and health care. To fulfill this demand, nanostructured metal oxides can be used as active materials for chemical/gas sensors due to their high crystallinity, remarkable physical/chemical properties, ease of synthesis, and low cost. In particular, (1D) one-dimensional metal oxides nanostructures, such as nanowires, exhibit a fast response, selectivity, and stability due to their high surface-to-volume ratio, well-defined crystal orientations, controlled unidirectional electrical properties, and self-heating phenomenon. Moreover, with the availability of large-scale production methods for nanowire growth such as thermal oxidation and evaporation-condensation growth, the development of highly efficient, low cost, portable, and stable chemical sensing devices is possible. In the last two decades, tremendous advances have been achieved in 1D nanostructured gas sensors ever since the pioneering work by Comini on the development of a SnO2 nanobelt for gas sensor applications in 2002, which is one such example from which many researchers began to explore the field of 1D-nanostructure-based chemical/gas sensors. The Sensor Laboratory (University of Brescia) has made major contributions to the field of metal oxide nanowire chemical/gas-sensing devices. Over the years, different metal oxides such as SnO2, ZnO, WO3, NiO, CuO, and their heterostructures have been grown for their nanowire morphology and successfully integrated into chemoresistive gas-sensing devices. Hence in this invited feature article, Sensor Laboratory research on the synthesis of metal oxide nanowires and novel heterostructures and their characterization and gas-sensing performance during exposure to different gas analytes has been presented. Moreover, some new strategies such as branched-like nanowire heterostructures and core-shell nanowire structures adopted to enhance the performance of nanowire-based chemical sensor are presented in detail.

Dataset Information

Nanostructured Chemiresistive Gas Sensors for Medical Applications.

Publications

Nanostructured Chemiresistive Gas Sensors for Medical Applications.

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