Ontology highlight
ABSTRACT:
SUBMITTER: Tugume L
PROVIDER: S-EPMC6387427 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Tugume Lillian L Rhein Joshua J Hullsiek Kathy Huppler KH Mpoza Edward E Kiggundu Reuben R Ssebambulidde Kenneth K Schutz Charlotte C Taseera Kabanda K Williams Darlisha A DA Abassi Mahsa M Muzoora Conrad C Musubire Abdu K AK Meintjes Graeme G Meya David B DB Boulware David R DR
The Journal of infectious diseases 20190201 6
<h4>Background</h4>Cryptococcal meningitis can occur in persons with less-apparent immunosuppression. We evaluated clinical characteristics and outcomes of persons with HIV-related Cryptococcus presenting with higher CD4 counts.<h4>Methods</h4>We enrolled 736 participants from 2 prospective cohorts in Uganda and South Africa from November 2010 to May 2017. We compared participants with CD4 <50, 50-99, or ≥100 cells/μL by clinical characteristics, cerebrospinal fluid (CSF) parameters, and 18-week ...[more]