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Efficiency of platelet-rich plasma on acellular dermal matrix application with coronally advanced flap in the treatment of multiple adjacent gingival recessions: A randomized controlled clinical trial.

ABSTRACT: Background/Purpose:The aim of this study was to evaluate the effectiveness of platelet rich plasma (PRP) combined with coronally advanced flap plus acellular dermal matrix application (CAF + ADM) in the treatment of multiple adjacent gingival recessions (MAGRs). Materials and methods:12 patients with 84 Miller Class I or II recession defects were participated. Sites were randomly assigned into CAF + ADM + PRP or CAF + ADM groups. Gingival recession depth (GRD), recession width (GRW), width of keratinized tissue (WKT), creeping attachment (CRA), root coverage (RC) as well as plaque index (PI), gingival index (GI), probing depth (PD), and clinical attachment level (CAL) were recorded at baseline and 3rd,6th and 12th months postoperatively. The data were analyzed statistically. Results:GRD and GRW values were statistically higher in group CAF + ADM compared to the CAF + ADM + PRP group at 6th and 12th month (P < 0.05). CRA showed statistically significant increases in 3rd, 6th and 12th months with regard to the baseline in CAF + ADM + PRP group (P < 0.05), however CRA remained stable in CAF + ADM group at 6th and 12th month. The mean RC% was 77.9% and 69.4% for the CAF + ADM + PRP and CAF + ADM groups, respectively, at 12th month (P < 0.05). GRD reduction was statistically greater in the maxillary teeth treated with CAF + ADM + PRP compared to mandibular teeth treated with CAF + ADM at 12 months. Conclusion:Our data suggested that addition of PRP to CAF + ADM in the treatment of MAGRs significantly improved the clinical outcomes, according to 1-year follow-up results.(Clinicaltrials.gov identification NCT03043638).

SUBMITTER: Cetiner D

PROVIDER: S-EPMC6388830 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature

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Efficiency of platelet-rich plasma on acellular dermal matrix application with coronally advanced flap in the treatment of multiple adjacent gingival recessions: A randomized controlled clinical trial.

Çetiner Deniz D Gökalp Kalabay Pelin P Özdemir Burcu B Çankaya Zeynep Turgut ZT

Journal of dental sciences 20180203 3

<h4>Background/purpose</h4>The aim of this study was to evaluate the effectiveness of platelet rich plasma (PRP) combined with coronally advanced flap plus acellular dermal matrix application (CAF + ADM) in the treatment of multiple adjacent gingival recessions (MAGRs).<h4>Materials and methods</h4>12 patients with 84 Miller Class I or II recession defects were participated. Sites were randomly assigned into CAF + ADM + PRP or CAF + ADM groups. Gingival recession depth (GRD), recession width (GR ...[more]

PMID: 30895121

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Project description:Background: The importance of esthetics has escalated over the years. The purpose of any perioplastic surgery is to address gingival recession while ensuring predictable root coverage and a pleasing appearance. An array of surgical procedures have been recommended for the management of recession defects. The present study compares the clinical and patient related outcome measures of coronally advanced flap with chorion membrane and connective tissue graft in the management of multiple adjacent gingival recessions. Methods: The study was a prospective randomized controlled trial which included eight systemically healthy patients with an age range of 30-44 years with 36 labial/buccal, multiple adjacent, Cairo's RT1 gingival recession defects, bilaterally. CAF+CM was performed on one side whereas CAF+CTG was performed on the other side. The two groups were compared clinically at three and six months postoperatively. Results: There was statistically significant decrease in recession depth, recession width, probing depth and clinical attachment level in both the groups from baseline to three and six months. However, intergroup comparisons revealed no statistically significant difference. At six months, both groups showed statistically significant improvements in keratinized tissue width and gingival thickness. The gingival thickness of the CAF+CM group increased significantly at three and six months. In terms of root coverage aesthetic score (RES), there was no significant difference observed between the two groups. In terms of patient reported outcome measures (PROMS), patients preferred the CAF+CM technique. Conclusion: Within the limits of the current study, the use of chorion membrane resulted in considerable root coverage and increased gingival thickness. Periodontal regeneration can be facilitated by the distinctive features of the chorion membrane. Coronally advanced flap plus chorion membrane is a novel approach for root coverage procedures.

Dataset Information

Efficiency of platelet-rich plasma on acellular dermal matrix application with coronally advanced flap in the treatment of multiple adjacent gingival recessions: A randomized controlled clinical trial.

Publications

Efficiency of platelet-rich plasma on acellular dermal matrix application with coronally advanced flap in the treatment of multiple adjacent gingival recessions: A randomized controlled clinical trial.

Similar Datasets

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