Gender differences in the prevalence of congenital heart disease in Down's syndrome: a brief meta-analysis.
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ABSTRACT:
SUBMITTER: Diogenes TCP
PROVIDER: S-EPMC6389118 | biostudies-literature | 2017 Oct
REPOSITORIES: biostudies-literature
Publications
Gender differences in the prevalence of congenital heart disease in Down's syndrome: a brief meta-analysis.
Diogenes Tereza Cristina Pinheiro TCP Mourato Felipe Alves FA de Lima Filho José Luiz JL Mattos Sandra da Silva SDS
BMC medical genetics 20171006 1
<h4>Background</h4>Down's syndrome (DS) affects one per 700 live births and congenital heart disease (CHD) occurs in 40-60% of these patients. Contributing factors to the association between DS and CHD are being unraveled. Gender could be one of them.<h4>Methods</h4>We performed a meta-analysis of CHD prevalence in DS, separated by gender. Three search engines were used and 578 articles were reviewed. Twelve articles were included.<h4>Results</h4>Quantitative analysis showed a higher prevalence ...[more]
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