Hemodynamic effects of acute hyperoxia: systematic review and meta-analysis.

ABSTRACT:

Background

In clinical practice, oxygen is generally administered to patients with the intention of increasing oxygen delivery. Supplemental oxygen may, however, cause arterial hyperoxia, which is associated with hemodynamic alterations. We performed a systematic review and meta-analysis of the literature to determine the effect of hyperoxia on central hemodynamics and oxygen delivery in healthy volunteers and cardiovascular-compromised patients.

Methods

PubMed and EMBASE were searched up to March 2017. Studies with adult humans investigating changes in central hemodynamics or oxygen delivery induced by acute normobaric hyperoxia were included. Studies focusing on lung, retinal, or brain parameters were not included. We extracted subject and oxygen exposure characteristics,

SUBMITTER: Smit B 

PROVIDER: S-EPMC6389225 | biostudies-literature | 2018 Feb

REPOSITORIES: biostudies-literature