Dataset Information

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.

ABSTRACT: An individual's dietary and supplement strategies can influence markedly their physical performance. Personalized nutrition in athletic populations aims to optimize health, body composition, and exercise performance by targeting dietary recommendations to an individual's genetic profile. Sport dietitians and nutritionists have long been adept at placing additional scrutiny on the one-size-fits-all general population dietary guidelines to accommodate various sporting populations. However, generic "one-size-fits-all" recommendations still remain. Genetic differences are known to impact absorption, metabolism, uptake, utilization and excretion of nutrients and food bioactives, which ultimately affects a number of metabolic pathways. Nutrigenomics and nutrigenetics are experimental approaches that use genomic information and genetic testing technologies to examine the role of individual genetic differences in modifying an athlete's response to nutrients and other food components. Although there have been few randomized, controlled trials examining the effects of genetic variation on performance in response to an ergogenic aid, there is a growing foundation of research linking gene-diet interactions on biomarkers of nutritional status, which impact exercise and sport performance. This foundation forms the basis from which the field of sport nutrigenomics continues to develop. We review the science of genetic modifiers of various dietary factors that impact an athlete's nutritional status, body composition and, ultimately athletic performance.

SUBMITTER: Guest NS

PROVIDER: S-EPMC6389634 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.

Guest Nanci S NS Horne Justine J Vanderhout Shelley M SM El-Sohemy Ahmed A

Frontiers in nutrition 20190219

An individual's dietary and supplement strategies can influence markedly their physical performance. Personalized nutrition in athletic populations aims to optimize health, body composition, and exercise performance by targeting dietary recommendations to an individual's genetic profile. Sport dietitians and nutritionists have long been adept at placing additional scrutiny on the one-size-fits-all general population dietary guidelines to accommodate various sporting populations. However, generic ...[more]

PMID: 30838211

Similar Datasets

Project description:The relationship between nutrition and genes has long been hinted at and sometimes plainly associated with certain diseases. Now, after many years of research and coincidental findings, it is believed that this relationship, termed "Nutrigenomics," is certainly a factor of major importance in various conditions. In this review article, we discuss nutrigenomics, starting with basics definitions and enzymatic functions and ending with its palpable association with cancer. Now, diet is basically what we eat on a daily basis. Everything that enters through our alimentary tract ends up broken down to minute molecules and amino acids. These molecules interact with our microbiome and genome in discreet ways. For instance, we demonstrate how proper intake of probiotics enhances beneficial bacteria and may alleviate IBS and prevent colorectal cancer on the long term. We also show how a diet rich in folic acid is essential for methylenetetrahydrofolate reductase (MTHFR) function, which lowers risk of colorectal cancer. Also, we discuss how certain diets were associated with development of certain cancers. For example, red and processed meat are highly associated with colorectal and prostate cancer, salty diets with stomach cancer, and obesity with breast cancer. The modification of these diets significantly lowered the risk and improved prognosis of these cancers among many others. We also examined how micronutrients had a role in cancer prevention, as vitamin A and C exert anti-carcinogenic effects through their function as antioxidants. In addition, we show how folic acid prevent DNA mutations by enhancing protein methylation processes. Finally, after a systematic review of myriad articles on the etiology and prevention of cancer, we think that diet should be a crucial feature in cancer prevention and treatment programs. In the future, healthy diets and micronutrients may even be able to successively alter the liability to genetic mutations that result in cancer. It also will play a role in boosting treatment and improving prognosis of diagnosed cancers.

Project description:BackgroundThe tool kits of bibliometrics and science mapping provide a standard methodology to map the knowledge base of specific fields of science. The aim of the present research is the analysis of the recent international trends of sport nutrition science, as well as the primary identification of the research topics and results of sport nutrition science via enhanced bibliometric methods for the 2000-2018 time period.MethodsAltogether, 3889 publications were included in this study. We identified the most relevant sport nutrition topics by running a community detection algorithm on the proximity network constructed via network text analysis. The key issues and key concepts of sport nutrition topics as well as their relations were evaluated via network analysis. Besides, we carried a chronological analysis of topics out and a scientometric evaluative analysis was also created.ResultsWe identified the four main basic groups from which the 18 most characteristics topics were analyzed. The 18 topics are the following: 'soccer and physiology', 'carbohydrate metabolism', 'muscle physiology: alkalosis and acidosis', 'muscle mass gain and dietary supplementation', 'fluid balance and hydration', 'dietary intake and nutrition knowledge', 'determination of energy need of athletes', 'bone health and female athlete triad', 'hydration strategy', 'body weight management', 'nutritional strategies and human skeletal muscle', 'dietary supplementation of nitrates', 'oxidative stress and dietary supplement use', 'dietary supplement use and doping', 'oxidative stress and inflammation and dietary antioxidants', 'exercise adaptation and nutritional strategies', 'gut microbiota', 'celiac disease'. Regarding the size of the topic, researches on sport nutrition science have put the focus on the following three groups: 'muscle mass gain and dietary supplementation', 'carbohydrate metabolism', 'oxidative stress and dietary supplement use'. The greatest scientific impact can be ascribed to the following topics: 'nutritional strategies and human skeletal muscle', 'dietary supplementation of nitrates', 'body weight management', and 'gut microbiota'.ConclusionsScientific output on sport nutrition has continuously been rising between 2000 and 2018. The ratio of topics related to sport nutrition but predominantly connected to basic research has decreased significantly within all publications. The results of this study confirm the role of science mapping in the identification of specific research topics and primary research directions in the field of sport nutrition science.

Dataset Information

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.

Publications

Sport Nutrigenomics: Personalized Nutrition for Athletic Performance.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets