Identification of Cancer Hallmarks Based on the Gene Co-expression Networks of Seven Cancers.
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ABSTRACT:
SUBMITTER: Yu LH
PROVIDER: S-EPMC6389798 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Identification of Cancer Hallmarks Based on the Gene Co-expression Networks of Seven Cancers.
Yu Ling-Hao LH Huang Qin-Wei QW Zhou Xiong-Hui XH
Frontiers in genetics 20190219
Identifying the hallmarks of cancer is essential for cancer research, and the genes involved in cancer hallmarks are likely to be cancer drivers. However, there is no appropriate method in the current literature for identifying genetic cancer hallmarks, especially considering the interrelationships among the genes. Here, we hypothesized that "dense clusters" (or "communities") in the gene co-expression networks of cancer patients may represent functional units regarding cancer formation and prog ...[more]
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