Ontology highlight
ABSTRACT:
SUBMITTER: Phan N
PROVIDER: S-EPMC6389967 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Phan Nhan N Hong Jenny J JJ Tofig Bobby B Mapua Matthew M Elashoff David D Moatamed Neda A NA Huang Jin J Memarzadeh Sanaz S Damoiseaux Robert R Soragni Alice A
Communications biology 20190225
Tumor organoids maintain cell-cell interactions, heterogeneity, microenvironment, and drug response of the sample they originate from. Thus, there is increasing interest in developing tumor organoid models for drug development and personalized medicine applications. Although organoids are in principle amenable to high-throughput screenings, progress has been hampered by technical constraints and extensive manipulations required by current methods. Here we introduce a miniaturized method that use ...[more]