Short-course versus long-course oral antibiotic treatment for infections treated in outpatient settings: a review of systematic reviews.

ABSTRACT:

Purpose

To summarize the evidence comparing the effectiveness of short and long courses of oral antibiotics for infections treated in outpatient settings.

Methods

We identified systematic reviews of randomized controlled trials for children and adults with bacterial infections treated in outpatient settings from Medline, Embase, CINAHL, Cochrane Database of Systematic Reviews and The Database of Review of Effects. Data were extracted on the primary outcome of clinical resolution and secondary outcomes.

Results

We identified 30 potential reviews, and included 9. There was no difference in the clinical cure for children treated with short or long course antibiotics for Group A streptococcal tonsillopharyngitis (OR 1.03, 95% CI:0.97, 1.11); community acquired pneumonia (

SUBMITTER: Dawson-Hahn EE 

PROVIDER: S-EPMC6390420 | biostudies-literature | 2017 Sep

REPOSITORIES: biostudies-literature