Two grass pollen tablets commercially available for allergy immunotherapy display different IgE epitope repertoires.

ABSTRACT:

Background

The distribution of Pooideae species varies across Europe. Especially, Timothy is less represented in Southern than in Northern Europe. Since allergenic cross-reactivity between pollens from different grasses is only partial, grass pollen-allergic patients are expected to display different sensitization profiles, with specific IgE directed against different combinations of allergenic epitopes, depending on their living places in Europe and the grasses they are exposed to. In this context, this study aimed at comparing two tablets commercially available for allergy immunotherapy, namely a 5-grass (Cocksfoot, Meadow-grass, Rye-grass, Sweet vernal-grass and Timothy) and a 1-grass (Timothy) pollen tablets, for their ability to represent the sensitization profiles of patients

SUBMITTER: Batard T 

PROVIDER: S-EPMC6391756 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature