Risk of all-cause and CHD mortality in women versus men with type 2 diabetes: a systematic review and meta-analysis.

ABSTRACT:

Objective

Previous studies have shown sex-specific differences in all-cause and CHD mortality in type 2 diabetes. We performed a systematic review and meta-analysis to provide a global picture of the estimated influence of type 2 diabetes on the risk of all-cause and CHD mortality in women vs men.

Methods

We systematically searched PubMed, EMBASE and Web of Science for studies published from their starting dates to Aug 7, 2018. The sex-specific hazard ratios (HRs) and their pooled ratio (women vs men) of all-cause and CHD mortality associated with type 2 diabetes were obtained through an inverse variance-weighted random-effects meta-analysis. Subgroup analyses were used to explore the potential sources of heterogeneity.

Results

The 35 analyzed prospective cohort studi

SUBMITTER: Xu G 

PROVIDER: S-EPMC6391911 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature