Ontology highlight
ABSTRACT:
SUBMITTER: Guo L
PROVIDER: S-EPMC6393485 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Guo Ling L Wang Xiaoxiao X Yuan Jifan J Zhu Meishu M Fu Xiaobing X Xu Ren-He RH Wu Chuanyue C Wu Yaojiong Y
Scientific reports 20190227 1
The genesis of the hair follicle relies on signals derived from mesenchymal cells in the dermis during skin morphogenesis and regeneration. Multipotent skin-derived precursors (SKPs), which exhibit long term proliferation potential when being cultured in spheroids, have been shown to induce hair genesis and hair follicle regeneration in mice, implying a therapeutic potential of SKPs in hair follicle regeneration and bioengineering. However, the hair-inductive property of SKPs declines progressiv ...[more]