Ontology highlight
ABSTRACT:
SUBMITTER: Hearn NL
PROVIDER: S-EPMC6394071 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
BMC genomics 20190228 1
<h4>Background</h4>Altered epigenetic profiles are a feature of intestinal diseases, including ulcerative colitis and Crohn's disease. DNA methylation studies in these diseases have utilised intestinal mucosal tissue or blood which can be difficult to collect, particularly for large-scale research studies. Saliva is an attractive alternative for epigenetic studies as it is easy to collect and provides high quality methylation profiles. The aim of the study was to determine the utility of saliva ...[more]