Ontology highlight
ABSTRACT:
SUBMITTER: Rajani KR
PROVIDER: S-EPMC6395389 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Rajani Karishma R KR Carlstrom Lucas P LP Parney Ian F IF Johnson Aaron J AJ Warrington Arthur E AE Burns Terry C TC
Frontiers in oncology 20190222
Glioblastoma is the most common adult primary brain tumor and carries a dismal prognosis. Radiation is a standard first-line therapy, typically deployed following maximal safe surgical debulking, when possible, in combination with cytotoxic chemotherapy. For other systemic cancers, standard of care is being transformed by immunotherapies, including checkpoint-blocking antibodies targeting CTLA-4 and PD-1/PD-L1, with potential for long-term remission. Ongoing studies are evaluating the role of im ...[more]