Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective.
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ABSTRACT:
SUBMITTER: Ten Brinke A
PROVIDER: S-EPMC6395407 | biostudies-literature | 2019
REPOSITORIES: biostudies-literature
Publications
Ways Forward for Tolerance-Inducing Cellular Therapies- an AFACTT Perspective.
Ten Brinke Anja A Martinez-Llordella Marc M Cools Nathalie N Hilkens Catharien M U CMU van Ham S Marieke SM Sawitzki Birgit B Geissler Edward K EK Lombardi Giovanna G Trzonkowski Piotr P Martinez-Caceres Eva E
Frontiers in immunology 20190222
Clinical studies with cellular therapies using tolerance-inducing cells, such as tolerogenic antigen-presenting cells (tolAPC) and regulatory T cells (Treg) for the prevention of transplant rejection and the treatment of autoimmune diseases have been expanding the last decade. In this perspective, we will summarize the current perspectives of the clinical application of both tolAPC and Treg, and will address future directions and the importance of immunomonitoring in clinical studies that will r ...[more]
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