Ontology highlight
ABSTRACT:
SUBMITTER: Shen D
PROVIDER: S-EPMC6395898 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
Antimicrobial agents and chemotherapy 20190226 3
Here, we report a multidrug-resistant hypervirulent <i>Klebsiella pneumoniae</i> (MDR-HvKP) strain of sequence type 23 (ST23) with a rare hybrid plasmid harboring virulence genes and <i>bla</i><sub>CTX-M-24</sub>, and we analyze the genetic basis for relationship between genotypes and MDR-hypervirulence phenotypes. Further analysis indicates that the hybrid plasmid is formed by IS<i>903D</i>-mediated intermolecular transposition of the <i>bla</i><sub>CTX-M-24</sub> gene into the virulence plasmi ...[more]