Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults.
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ABSTRACT:
SUBMITTER: Lee MK
PROVIDER: S-EPMC6396524 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Publications
Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults.
Lee Mi Kyeong MK Xu Cheng-Jian CJ Carnes Megan U MU Nichols Cody E CE Ward James M JM Kwon Sung Ok SO Kim Sun-Young SY Kim Woo Jin WJ London Stephanie J SJ
Clinical epigenetics 20190228 1
<h4>Background</h4>Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To evaluate associations of long-term air pollution exposure with DNA methylation in blood, we conducted an epigenome-wide association study in a Korean chronic obstructive pulmonary disease cohort (N = 100 including 60 cases) using Illumina's Infinium HumanMethylation450K Beadc ...[more]
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