Intestinal transcriptional profiling reveals fava bean-induced immune response in DBA/1 mice.
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ABSTRACT:
SUBMITTER: Du G
PROVIDER: S-EPMC6396536 | biostudies-literature | 2019 Mar
REPOSITORIES: biostudies-literature
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Intestinal transcriptional profiling reveals fava bean-induced immune response in DBA/1 mice.
Du Guankui G Xiao Man M Zhu Qiwei Q Zhou Chen C Wang Ao A Cai Wangwei W
Biological research 20190301 1
<h4>Background</h4>Fava beans (FBs) have long been used as food, and their principal disadvantage is derived from their haemotoxicity. We hypothesized that FB ingestion alters the intestinal gene expression pattern, thereby inducing an immune response.<h4>Results</h4>In-depth sequence analysis identified 769 differentially expressed genes (DEGs) associated with the intestine in FB-treated DBA/1 mouse intestines. The identified genes were shown to be associated with biological processes (such as ...[more]
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